FibroTest/FibroSure Scientific Publications
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1041 HCV Multicentric US trials using FibroTest to diagnose cirrhosis in HCV Twelve weeks of sofosbuvir plus ribavirin is effective for treatment of genotype 2 HCV in difficult to treat u.s. veterans with cirrhosis – Results of the VALORHCV study. Samuel B. Ho1, Monto A, et al. FibroTest is used to identify cirrhotic in an open-label study to evaluate the safety and efficacy of 12 weeks of SOF+RBV in genotype-2 HCV infected veterans. The study was conducted at 15 U.S. VA sites: 15% of subjects were African American, 9% Hispanic, among them with vascular (71.2%) or metabolic (62.1%) comorbidities. ✓ Cirrhosis was diagnosed by FibroTest (58%), FibroScan (26%), biopsy (12%), and imaging (5%). VALORHCV is the largest prospective study of SOF+RBV in GT2 cirrhotic and confirms the effectiveness of all-oral SOF+RBV for 12 weeks in this difficult to treat population.
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FibroTest/FibroSure Scientific Publications
1162 NAFLD Diagnostic performance of FibroTest, SteatoTest, and ActiTest in patients with NAFLD using the SAF-score as histological reference M Munteanu, D Tiniakos, Q Anstee, F Charlotte, G Marchesini, E Bugianesi, MH. Trauner, CP. Oliveira, C Day, JF Dufour, S Bellentani, Y Ngo, S Traussnigg, P Bedossa, V Ratziu, T Poynard. The study aimed to improve the validation of three blood tests used i...
متن کاملNoninvasive Markers of Hepatic Fibrosis in Chronic Hepatitis B
A serum biomarker (FibroTest; Biopredictive, Paris, France; FibroSure; LabCorp, Burlington, USA) and liver stiffness measurement (LSM) by Fibroscan (Echosens, Paris, France) have been extensively validated in chronic hepatitis C. This review updates the clinical validation of serum biomarkers and LSM in patients with chronic hepatitis B (CHB). One meta-analysis combined all published studies an...
متن کاملOverview of the diagnostic value of biochemical markers of liver fibrosis (FibroTest, HCV FibroSure) and necrosis (ActiTest) in patients with chronic hepatitis C
SUMMARY: BACKGROUND: Recent studies strongly suggest that due to the limitations and risks of biopsy, as well as the improvement of the diagnostic accuracy of biochemical markers, liver biopsy should no longer be considered mandatory in patients with chronic hepatitis C. In 2001, FibroTest ActiTest (FT-AT), a panel of biochemical markers, was found to have high diagnostic value for fibrosis (FT...
متن کاملThe use of transient elastography and FibroTest for monitoring hepatotoxicity in patients receiving methotrexate for psoriasis.
IMPORTANCE There is a need for noninvasive tools to monitor hepatotoxicity in patients with psoriasis who are receiving methotrexate sodium. OBJECTIVE To evaluate the use of transient elastography (TE) and FibroTest (FibroSURE in the United States), an indirect serum marker of fibrosis, in this population. DESIGN, SETTING, AND PARTICIPANTS Patients receiving methotrexate therapy for psorias...
متن کاملDiagnostic value of biochemical markers (FibroTest-FibroSURE) for the prediction of liver fibrosis in patients with non-alcoholic fatty liver disease
BACKGROUND Liver biopsy is considered as the gold standard for assessing non-alcoholic fatty liver disease (NAFLD) histologic lesions. The aim of this study was to determine the diagnostic utility of non-invasive markers of fibrosis, validated in chronic viral hepatitis and alcoholic liver disease (FibroTest, FT), in patients with NAFLD. METHODS 170 patients with suspected NAFLD were prospect...
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